If you are aiming for totally maximizing the size of your muscles, you will likely need to add supplements to your exercise and diet plans. Pre-exhausting muscles is a great way to build the most stubborn groups. For example, your biceps might be fatigued before your lats on rows. An exercise that isolates and works only your lats, performed before your workout, allows you to avoid this problem. Because your lats will have tired somewhat before you ever start doing rows, your biceps will be less likely to limit you.